IRB identifies the receptor of the virus responsible of the most common cause of permanent births defects

Potent anti-pentamer monoclonal antibodies prevent HCMV from binding to its receptor Nrp2
Potent anti-pentamer monoclonal antibodies prevent HCMV from binding to its receptor Nrp2

Institutional Communication Service

27 July 2018

A collaborative effort between the Institute for Research in Biomedicine (IRB, affiliated to USI Università della Svizzera italiana), Genentech (U.S.A.), and the Institute of Molecular System Biology at ETH Zurich led to the identification of Neuropilin 2 as the central receptor for the pentameric complex of Human cytomegalovirus (HCMV). This study was published today in the renowned scientific journal Cell. The project was jointly conceived and supervised by Laurent Perez from the IRB and Claudio Ciferri from Genentech.

Full press report at: www.irb.usi.ch

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